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  • br S Morishita et al br size was small

    2020-08-12


    S. Morishita, et al.
    size was small. Thus, we did not show the effect of different cancer types on the relation between balance function and muscle strength. In future studies, we should present the possible mechanisms of balance function in cancer survivors with a larger sample size.
    6. Conclusion
    Breast cancer survivors had significantly lower hand grip strength and Mini-BESTest scores than healthy women. Additionally, balance function (as assessed by the Mini-BESTest and TUG test) and grip strength were correlated in breast cancer survivors, but not in healthy women. Hand grip strength and Mini-BESTest scores were not sig-nificantly different in non-breast cancer survivors compared to healthy participants. Additionally, balance function and knee extension strength were correlated in non-breast cancer survivors. We believe the current findings contribute to the understanding of the changes in balance function and muscle strength PER977 in cancer survivors.
    Funding
    The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was partly supported by a Grant-in-Aid for Niigata University of Health and Welfare, as well as the M.D. Anderson Cancer Center Support Grant CA 016672.
    Declaration of Competing Interest
    The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
    Acknowledgments
    The authors are grateful to the study participants and physical therapy students for their help in the collection of muscle strength and balance function data. This study was partly supported by a grant-in-aid for Niigata University of Health and Welfare, as well as an MD Anderson Cancer Center support grant (CA 016672).
    References
    Carmeli, E., Imam, B., Levi, R., Merrick, J., 2013. Hand grip strength is associated with body sway rate among older adults with intellectual disability. Journal of Policy and Practice in Intellectual Disabilities 10, 321–325. Chen, H.Y., Tang, P.F., 2016. Factors contributing to single- and dual-task timed “Up & amp; Go” test performance in middle-aged and older adults who are active and dwell in the community. Phys. Ther. 96, 284–292. Foley, M.P., Hasson, S.M., 2016. Effects of a community-based multimodal exercise program on health-related physical PER977 and physical function in breast cancer survivors: a pilot study. Integr. Cancer Ther. 15, 446–454.
    Ibrahim, M., Muanza, T., Smirnow, N., Sateren, W., Fournier, B., Kavan, P., Palumbo, M., Dalfen, R., Dalzell, M.A., 2018. A pilot randomized controlled trial on the effects of a progressive exercise program on the range of motion and upper extremity grip strength in young adults with breast cancer. Clin. Breast Cancer 18, e55–e64.
    Morishita, S., Kaida, K., Aoki, O., Yamauchi, S., Wakasugi, T., Ikegame, K., Ogawa, H., Domen, K., 2015. Balance function in patients who had undergone allogeneic he-matopoietic stem cell transplantation. Gait Posture 42, 406–408. Ness, K.K., Jones, K.E., Smith, W.A., Spunt, S.L., Wilson, C.L., Armstrong, G.T., Srivastava, D.K., Robison, L.L., Hudson, M.M., Gurney, J.G., 2013. Chemotherapy-related neu-ropathic symptoms and functional impairment in adult survivors of extracranial solid tumors of childhood: results from the St. Jude Lifetime Cohort Study. Arch. Phys.
    Journal of Coloproctology
    Original Article
    Assessment of the non-surgical treatment of patients with rectal cancer who underwent neoadjuvant treatment with chemotherapy and radiotherapy at the oncology department
    Meyline Andrade Lima a, Eduardo Dias de Moraes b, Elisa Yumi Saito c, Daniela Galvao Barros d, Pamela Souza Almeida Malta e,
    Isabela Maria Alves de Almeida Oliva f, Carlos Ramon Silveira Mendes a,g,∗
    a Hospital Santa Izabel – Santa Casa da Bahia, Servic¸ o de Coloproctologia, Salvador, BA, Brazil b Núcleo de Oncologia da Bahia, Salvador, BA, Brazil
    c Hospital Santa Izabel – Santa Casa da Bahia, Servic¸ o de Radioterapia, Salvador, BA, Brazil d Hospital Santa Izabel – Santa Casa da Bahia, Servic¸ o de Oncologia Clínica, Salvador, BA, Brazil e Clinica AMO, Salvador, BA, Brazil f Obras Sociais de Irmã Dulce (OSID), Salvador, BA, Brazil g Universidade de São Paulo (USP), Salvador, BA, Brazil
    Article history:
    Keywords:
    Quality of life
    Rectal surgery
    Wait-and-see policy
    Rectal cancer
    ∗ Corresponding author. 
    Objective: To describe the partial results of a study in patients with rectal cancer who under-went neoadjuvant treatment with chemotherapy and radiotherapy regarding the rate of complete clinical response, disease-free survival, anorectal function, and quality of life.
    Material and methods: This was a prospective study from June 2015 to June 2018, in patients with low- or mid-rectum adenocarcinoma and clinical stage II or III, treated with radiother-apy and chemotherapy (IMRT 54 Gy for six weeks) concomitant with 5-fluorouracil (5-FU) 380 mg/m2 and folinic acid (LV) 20 mg/m2 for five days in the first and fifth weeks and two cycles after radiotherapy (5-FU 400 mg/m2 and LV 20 mg/m2 ) every 28 days. After the treat-ment, clinical examination, rectosigmoidoscopy, pelvic magnetic resonance imaging, chest and upper abdomen computed tomography, and CEA testing were performed. Resection surgery was performed in those with incomplete clinical response (iCR). Those with com-plete clinical response (cCR) are under observation (wait-and-see policy). Manometry and scintigraphic function and quality of life scales were collected before treatment and at 30 and 90 days after the end of treatment.